‘Tumour-trained’ immune cells move from one tumour to another
Metastatic cancer, in which cancer has spread to other sites beyond the primary tumour, is responsible for almost all cancer deaths, and treatment options remain limited. While new immune therapies that help the body’s own immune T cells to attack cancer cells within tumours are showing promise in metastatic cancer, little is understood about how these therapies function.
Now, scientists at Sydney’s Garvan Institute of Medical Research have discovered that ‘tumour-trained’ immune cells — which have the potential to kill cancer cells — move from one tumour to another. The findings shed light on how immune therapies for cancer might work and suggest new approaches to developing anti-cancer immune therapies.