Human forebrain circuits under construction – in a dish
Autism-related errant migration of neurons corrected in patient-derived 3D “spheroids”
National Institutes of Health (NIH)-funded neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development. What’s more, they used it to discover and experimentally correct — in a petri dish — defective cell migration caused by an autism-related disorder.