DNA ‘typos’ may cause 66% of cancer mutations

Random, unpredictable DNA copying mistakes account for nearly two-thirds of the genetic changes that cause cancer—far more mutations than those triggered by heredity or by environmental factors like smoking or pollution, a study finds.

The study used a new mathematical model based on DNA sequencing and epidemiologic data from around the world.

The findings do not in any way suggest that we give up on healthy lifestyles and other strategies for minimizing the likelihood of cancer, say the researchers.

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